- A metalloproteinase, or
metalloprotease, is any
protease enzyme whose catalytic mechanism involves a metal. An
example is ADAM12
which plays a significant...
- von
Willebrand factor-cleaving
protease (VWFCP)—is a zinc-containing
metalloprotease enzyme that
cleaves von
Willebrand factor (vWf), a
large protein involved...
-
Castelhano AL (1995). "Matrilysin-inhibitor complexes:
common themes among metalloproteases". Biochemistry. 34 (20): 6602–10. doi:10.1021/bi00020a004. PMID 7756291...
-
characterized by a
particular domain organization featuring a pro-domain, a
metalloprotease, a disintegrin, a cysteine-rich, an epidermal-growth
factor like and...
-
Metalloprotease inhibitors are
cellular inhibitors of the
matrix metalloproteinases (MMPs). MMPs
belong to a
family of zinc-dependent
neutral endopeptidases...
- A
disintegrin and
metalloprotease 17 (ADAM17), also
called TACE (tumor
necrosis factor-α-converting enzyme), is a 70-kDa
enzyme that
belongs to the ADAM...
-
Transforming growth factor beta (TGF-β) is a
multifunctional cytokine belonging to the
transforming growth factor superfamily that
includes three different...
-
Tissue inhibitors of
metalloproteinases (TIMPs) are
specific endogenous protease inhibitors to the
matrix metalloproteinases.
There are four TIMPs; TIMP1...
-
Diagram of an
ectodomain shedding ADAM
metalloprotease....
- a Zn
supplementation for
increasing responsiveness to
therapeutic metalloproteases,
including increasing and/or
maximizing responsiveness and preventing...
