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Metacaspases are
members of the C14
class of
cysteine proteases and thus
related to caspases,
orthocaspases and paracaspases. The
metacaspases are...
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similar to
caspases than
metacaspases are,
indicating that this
group of
proteases diverged from
caspases from a
common metacaspase ancestor. [citation needed]...
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Orthocaspases is a sub-class in the C14
family of
cysteine proteases.
Similar to
metacaspases and paracaspases, the
orthocaspases cleave their protein substrates after...
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induced by
arginine and lysine-specific
caspase like
proteases called metacaspases.
Homology searches revealed a
close homology between caspases and the...
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cysteine protease caspase-1. In eukaryotes, a
plant serpin inhibits both
metacaspases and a papain-like
cysteine protease. Non-inhibitory
extracellular serpins...
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Wickner RB (2011). "Retraction for
Nemecek et al., A
prion of
yeast metacaspase homolog (Mca1p)
detected by a
genetic screen". Proc Natl Acad Sci U S...
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Koonin EV,
Dixit VM (October 2000). "Identification of
paracaspases and
metacaspases: two
ancient families of caspase-like proteins, one of
which plays a...
- V.; Dixit, V. M. (October 2000). "Identification of
paracaspases and
metacaspases: two
ancient families of caspase-like proteins, one of
which plays a...
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Cysteine 464 and
histidine 414 are
crucial for this activity. Like
metacaspases, the
paracaspase cleaves substrates after an
arginine residue. To date...