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Metacaspases are
members of the C14
class of
cysteine proteases and thus
related to caspases,
orthocaspases and paracaspases. The
metacaspases are...
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caspase and
metacaspase sequences occurred before the
divergence of eukaryotes.
Biology portal Apoptosis Apoptosome Bcl-2
Emricasan Metacaspase Paracaspase...
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related to
caspases present in
animals and
slime mold, in
contrast to
metacaspases,
which are
present in plants, fungi, and "protists". The phylogenetic...
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cysteine protease caspase-1. In eukaryotes, a
plant serpin inhibits both
metacaspases and a papain-like
cysteine protease. Non-inhibitory
extracellular serpins...
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Orthocaspases is a sub-class in the C14
family of
cysteine proteases.
Similar to
metacaspases and paracaspases, the
orthocaspases cleave their protein substrates after...
-
Wickner RB (2011). "Retraction for
Nemecek et al., A
prion of
yeast metacaspase homolog (Mca1p)
detected by a
genetic screen". Proc Natl Acad Sci U S...
- cell
activation and MALT lymphomas. His team
described the
family of
metacaspase proteases in
plants in a
paper published in 2000. In a
series of papers...
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Cysteine 464 and
histidine 414 are
crucial for this activity. Like
metacaspases, the
paracaspase cleaves substrates after an
arginine residue. To date...
-
Koonin EV,
Dixit VM (October 2000). "Identification of
paracaspases and
metacaspases: two
ancient families of caspase-like proteins, one of
which plays a...
