-
fatty acids to
replace glucose in
tissues such as the
brain that
cannot metabolize fatty acids. In
other organisms such as
plants and bacteria, this metabolic...
-
processes are
often facilitated by
enzymes such as drug
transporters or drug
metabolizing enzymes (discussed in-depth below).
Variation in DNA loci responsible...
- dealkylation. CYP2D6 also
activates some prodrugs. This
enzyme also
metabolizes several endogenous substances, such as N,N-Dimethyltryptamine, hydroxytryptamines...
-
Steroidogenic enzymes are
enzymes that are
involved in
steroidogenesis and
steroid biosynthesis. They are
responsible for the
biosynthesis of the steroid...
- The A****er system,
named after Wilbur Olin A****er, or
derivatives of this
system are used for the
calculation of the
available energy of foods. The system...
- and
intermediate metabolizers have
reduced metabolism of the drug as
compared to
extensive metabolizers;
patients with
these metabolizer types may have...
- 250% in ultra-rapid
metabolizers, 150% in
extensive metabolizers, 50% in
intermediate metabolizers, and 30% in poor
metabolizers.
Doxepin is a tricyclic...
- 18.1 L/h for CYP2D6 ultra-rapid
metabolizers,
extensive metabolizers,
intermediate metabolizers, and poor
metabolizers. Area-under-the-curve
levels of...
-
which preferentially metabolizes arachidonic acid to 12-HpETE but also to
substantial amounts of 15-HpETE, in that
metabolizes arachidonic acid almost...
- and
intermediate metabolizers have
reduced metabolism of the drug as
compared to
extensive metabolizers;
patients with
these metabolizer types may have...
