Definition of Mertansine. Meaning of Mertansine. Synonyms of Mertansine

Here you will find one or more explanations in English for the word Mertansine. Also in the bottom left of the page several parts of wikipedia pages related to the word Mertansine and, of course, Mertansine synonyms and on the right images related to the word Mertansine.

Definition of Mertansine

No result for Mertansine. Showing similar results...

Meaning of Mertansine from wikipedia

- Mertansine, also called DM1 (and in some of its forms emtansine), is a thiol-containing maytansinoid that for therapeutic purposes is attached to a monoclonal...
- Lorvotuzumab mertansine (IMGN901) is an antibody-drug conjugate. It comprises the CD56-binding antibody, lorvotuzumab (huN901), with a maytansinoid cell-killing...
- Cantuzumab mertansine (SB-408075; huC242-DM1) is an antibody-drug conjugate investigated to treat colorectal cancer and other types of cancer. It is a...
- Bivatuzumab mertansine is a combination of bivatuzumab, a humanized monoclonal antibody, and mertansine, a cytotoxic agent. It is designed for the treatment...
- (INN) bitolterol (INN) bitoscanate (INN) bivalirudin (INN) bivatuzumab mertansine (INN) Bivigam bixalomer (USAN, INN) bizelesin (INN) Bizengri Bkemv Blenoxane...
- approval. It consists of trastuzumab (Herceptin) linked to a cytotoxic agent mertansine (DM1), used in the treatment of HER2-positive metastatic breast cancer...
- It uses a more hindered disulfide linkage than cantuzumab mertansine. Cantuzumab mertansine ImmunoGen Inc, developer of DM4 based drugs World Health Organization...
- inhibitors monomethyl auristatin E (MMAE), monomethyl auristatin F (MMAF) and mertansine, DNA binder calicheamicin and topoisomerase 1 inhibitors SN-38 and exatecan...
- several cytotoxic agents, yielding antibody-drug conjugates : Cantuzumab mertansine Cantuzumab ravtansine "HuC242 binds to the extracellular domain of the...
- Axatilimab Belantamab mafodotin Bevacizumab Bivatuzumab mertansine§ Brontictuzumab§ Cantuzumab mertansine§ Cantuzumab ravtansine§ Cirmtuzumab Citatuzumab bogatox§...