-
Mercaptopurine (6-MP), sold
under the
brand name
Purinethol among others, is a
medication used for
cancer and
autoimmune diseases.
Specifically it is used...
- step that
azathioprine undergoes in the body is the
conversion to 6-
mercaptopurine (6-MP; see Pharmacokinetics),
which is
itself an
immunosuppressant prodrug...
- extensive, and are as follows:
Azathioprine and 6-
mercaptopurine:
Azathioprine is
metabolised to 6-
mercaptopurine which in turn is
inactivated by the action...
-
nonenzymatically cleaved to
mercaptopurine, that acts as a
purine analogue and an
inhibitor of DNA synthesis.
Mercaptopurine itself can also be administered...
-
Decitabine Doxifluridine Fludarabine Fluorouracil Gemcitabine Hydroxyurea Mercaptopurine Methotrexate Nelarabine Pemetrexed Tioguanine (formerly Thioguanine)...
-
transplantation to
control rejection reactions. It is
nonenzymatically cleaved to
mercaptopurine, a
purine analogue that
inhibits DNA synthesis. By
preventing the clonal...
-
Immunosuppressive drugs used with
ulcerative colitis include:
Mercaptopurine, also
known as 6-
Mercaptopurine, 6-MP and Purinethiol. Azathioprine, also
known as Imuran...
-
Health Organization's List of
Essential Medicines, such as amoxicillin,
mercaptopurine,
pyrimethamine and zidovudine. In 2012,
under prosecution by the United...
- are
marketed for this purpose.[citation needed]
Azathioprine and 6-
mercaptopurine (6-MP) are the most
commonly used
immunosuppressants for maintenance...
- fluorouracil, cyclophosphamide,
diethylstilbestrol diphosphate, L-DOPA,
mercaptopurine, mitomycin,
zidovudine Type IB
Metabolic tissues (liver, GI mucosal...