Definition of Meganucleases. Meaning of Meganucleases. Synonyms of Meganucleases

- human-sized genome). Meganucleases are therefore considered to be the most specific naturally occurring restriction enzymes. Among meganucleases, the LAGLIDADG...
- nucleases (TALEN), meganucleases and the clustered regularly interspaced short palindromic repeats (CRISPR/Cas9) system. Meganucleases, discovered in the...
- double stranded breaks (base editors). Meganucleases were first used in 1988 in mammalian cells. Meganucleases are endodeoxyribonucleases that function...
- pairs on average (4^6=4096). One unique family of nucleases is the meganucleases, which are characterized by having larger, and therefore less common...
- cell-po****tion. Meganucleases Meganucleases are operationally analogous to ZFN's. There are limitations inherent in their use such as the meganuclease vector design...
- activator-like effector nuclease (TALEN), oligonucleotide directed mutagenesis + meganucleases. Genome editing, a type of genetic engineering Gene therapy, the therapeutic...
- I is a homing endonuclease. The enzyme is used in biotechnology as a meganuclease. It recognises an 18-base pair sequence TAGGGATAACAGGGTAAT and leaves...
- engineering tools, such as meganucleases. The DNA binding region of a TAL effector can be combined with the cleavage domain of a meganuclease to create a hybrid...
- nonhomologous end-joining. There are four families of engineered nucleases: meganucleases, zinc finger nucleases, transcription activator-like effector nucleases...
- nuclease-based genome editing and a pioneer in the analysis and use of meganucleases to modify complex genomes. André Choulika was born in Beirut, Lebanon...