- A
megakaryocyte (from mega- 'large' karyo- 'cell nucleus' and -cyte 'cell') is a
large bone
marrow cell with a
lobated nucleus that
produces blood platelets...
- the bone
marrow cells that bud off
large numbers of platelets.
Megakaryocytopoiesis is the
cellular development process that
leads to
platelet production...
-
cloned in 1994.
Thrombopoietin was
shown to be the
major regulator of
megakaryocytopoiesis and
platelet formation. The
protein encoded by the c-mpl gene, CD110...
- S,
Tenza D, Caen JP (April 1990). "Negative
regulation of
human megakaryocytopoiesis by
human platelet factor 4 and beta thromboglobulin: comparative...
- IL-10.
Interleukin 11 (IL-11) is a
secreted protein that
stimulates megakaryocytopoiesis,
initially thought to lead to an
increased production of platelets...
- in
blood cells:
correlation with
various leukemias and
abnormal megakaryocytopoiesis".
Proceedings of the
National Academy of
Sciences of the
United States...
-
Thrombopoietin Kimura H,
Ohkoshi T,
Matsuda S,
Uchida T,
Kariyone S (1988). "
Megakaryocytopoiesis in
polycythemia vera:
characterization by
megakaryocytic progenitors...
-
Andreeff M,
Croce CM (March 2006). "MicroRNA
fingerprints during human megakaryocytopoiesis".
Proceedings of the
National Academy of
Sciences of the
United States...
-
Oshimi K,
Mizoguchi H (January 1992). "Interleukin-11
enhances human megakaryocytopoiesis in vitro". Blood. 79 (2): 327–31. doi:10.1182/blood.V79.2.327.327...
-
Cosman D,
Vainchenker W., « Mpl
ligand is a
humoral regulator of
megakaryocytopoiesis », Nature, 1994 jun 16;369(6481), p. 571-4
Methia N,
Louache F, Vainchenker...
