- megakaryocytopenia, i.e. low
numbers of
platelets and
megakaryocytes.
There is an
absence of
megakaryocytes in the bone
marrow with no ****ociated
physical abnormalities...
- of
platelets and
megakaryocytes by the mpl
receptor (CD 110).
Inside the
platelets it gets destro****,
while inside the
megakaryocytes it
gives the signal...
-
Increased entry of
megakaryocytes into the
systemic circulation.
Under normal cir****stances in
healthy individuals,
megakaryocytes that
arise from the...
-
granulocyte precursors and
megakaryocytes, with the
megakaryocytes prominent in
their number and in
their bizarre shapes.
Megakaryocytes are
believed to be involved...
-
platelet precursor that
undergoes endomitosis to form
megakaryocytes that have 8 to 64 nuclei.
Megakaryocytes shed
platelets into the bloodstream. β1-tubulin...
-
enlarged spleen. In ET,
megakaryocytes are more
sensitive to
growth factors.
Platelets derived from the
abnormal megakaryocytes are activated, which, along...
- have no cell nucleus; they are
fragments of
cytoplasm derived from the
megakaryocytes of the bone
marrow or lung,
which then
enter the circulation. Platelets...
-
Examination of the bone
marrow shows characteristic changes in the
megakaryocytes. They are more
numerous than usual,
small and mononuclear.
There may...
-
myeloid progenitor lineage.
Megakaryocyte–erythroid
progenitor cells must
commit to
becoming either platelet-producing
megakaryocytes via
megakaryopoiesis or...
- viruses.
Macrophages remove senescent erythrocytes, leukocytes, and
megakaryocytes by
phagocytosis and digestion.
Formation of new red
blood cells (RBCs)...
