- Historically,
medulloblastomas have been
classified as a
primitive neuroectodermal tumor (PNET), but it is now
known that
medulloblastoma is
distinct from...
-
model was used to
confirm p53 as one of the
genes involved in
human medulloblastomas, but
since only
about 10% of the
human tumors showed mutations in that...
-
Staging System and a
Megavoltage Radiotherapeutic Technic for
Cerebellar Medulloblastomas". Radiology. 93 (6): 1351–1359. doi:10.1148/93.6.1351. ISSN 0033-8419...
- (October 17, 2005 –
April 25, 2014) who had died two
months earlier from
medulloblastoma, a rare
tumor that
affects the
brain and
spinal cord.
Beginning in...
-
precursor cells,
often called blasts.
Examples are nephroblastoma,
medulloblastoma, and retinoblastoma. The
suffix -blastoma is used to
imply a tumor...
- wrestling-inspired
nicknames "Stone Crusher" and "The Crusher". He
developed medulloblastoma in
September 2009, when he was
three years old.
After his diagnosis...
- glioma,
medulloblastoma,
neuronal and
mixed neuronal-glial tumors, and ependymoma. In
children under 2,
about 70% of
brain tumors are
medulloblastomas, ependymomas...
-
Glioblastomas ~3%
Oligodendroglial tumors ~1.5%
Ependymal tumor ~9%
Medulloblastomas ~20%
Pineal tumors ~1.5%
Meningeal tumors ~1.2% Germ cell
tumors ~3%...
- rule are
those that
exhibit haploinsufficiency,
including PTCH in
medulloblastoma and NF1 in neurofibroma.
Another example is p27, a cell-cycle inhibitor...
-
activate Sonic hedgehog signaling predispose to
cancer of the
cerebellum (
medulloblastoma) in
humans with
Gorlin Syndrome and in
genetically engineered mouse...
