- 4-
Maleylacetoacetate (4-maleylacetoacetatic acid) is an
intermediate in the
metabolism of tyrosine. It is
converted to
fumarylacetoacetate by the enzyme...
- In enzymology,
maleylacetoacetate isomerase (EC 5.2.1.2) is an
enzyme that
catalyzes the
chemical reaction 4-
maleylacetoacetate ⇌ {\displaystyle \rightleftharpoons...
- is an
enzyme which catalyzes the
conversion of
homogentisate to 4-
maleylacetoacetate.
Homogentisate 1,2-dioxygenase or HGD is
involved in the catabolism...
-
incorporation of a
further O2 molecule,
maleylacetoacetate is created.
Fumarylacetoacetate is
created by
maleylacetoacetate cis-trans-isomerase
through rotation...
- is
formed through the
conversion of
maleylacetoacetate into
fumarylacetoacetate by the
enzyme maleylacetoacetate isomerase.
Fumarylacetoacetate hydrolase...
-
Glutathione S-transferase Zeta 1 (also
known as
maleylacetoacetate isomerase) is an
enzyme that in
humans is
encoded by the GSTZ1 gene on
chromosome 14...
-
metabolize the
homogentisic acid (generated from tyrosine) into 4-
maleylacetoacetate, and
homogentisic acid
levels in the
blood are 100-fold
higher than...
- ac****ulation of
upstream compounds in the
catabolic pathway.
These include maleylacetoacetate (MAA) and
fumarylacetoacetate (FAA). MAA and FAA are
converted to...
- GSTM4, GSTM5
Omega GSTO1, GSTO2 Pi GSTP1
Theta GSTT1, GSTT2, GSTT4 Zeta GSTZ1 (aka MAAI-
Maleylacetoacetate isomerase)
Microsomal MGST1, MGST2, MGST3...
- isomerases: EC
number Examples EC 5.2.1.1
Maleate isomerase EC 5.2.1.2
Maleylacetoacetate isomerase EC 5.2.1.4
Maleylpyruvate isomerase EC 5.2.1.5 Linoleate...
