- δ-lactone = 6-membered, etc.
Macrocyclic lactones are
known as
macrolactones. Look up
macrolactone in Wiktionary, the free dictionary. The
other suffix used...
- that
underwent transannular 5-exo-dig cyclization. The ansa-bridging
macrolactone was
constructed following the
first Sonogashira coupling,
using the Shiina...
- to form alcohol,
double bonds or
single bonds.
After cyclisation, the
macrolactone core
undergoes further modification by hydroxylation,
methylation and...
-
carbonyl center,
providing a
tetrahedral intermediate that
yields the
macrolactone product. One of the
first examples of this
protocol was
applied to the...
-
Habgood GJ,
DiPietro LV, et al. (November 2004). "Structurally
simplified macrolactone analogues of
halichondrin B".
Bioorganic &
Medicinal Chemistry Letters...
-
There are
various subclasses of
polyketides including: aromatics,
macrolactones/macrolides,
decalin ring containing, polyether, and polyenes. Polyketide...
-
glycosyltransferase responsible for the
attachment of TDP-D-desosamine to
macrolactones of
varied ring sizes.
Borisova SA, Liu HW (September 2010). "Characterization...
-
separate the diastereomers.
Epothilone B is a 16-membered
polyketide macrolactone with a
methylthiazole group connected to the
macrocycle by an olefinic...
- and B.
Their formulas are
respectively C22H31NO5S and C20H29NO5S. The
macrolactone ring on top that
contains double bonds is a
structural feature of the...
- then is
iteratively elongated with malonyl-CoA
units to
construct the
macrolactone backbone. At
modules 3 and 7, a
double bond
shift occurs in the elongation...
