Definition of MTORC. Meaning of MTORC. Synonyms of MTORC

- (GDC-0980) is a PI3K inhibitor (subunits α, δ, and γ) that also targets mTORC There are numerous cell signalling pathways that exhibit cross-talk with...
- than the mTORC1 signaling pathway. The functions of the components of the mTORC complexes have been studied using knockdowns and knockouts and were found...
- counterpart called cTORC to explain why cancer therapies targeting only mTORC have been unsuccessful. "Platanias Receives AHEPA Academy of Achievement...
- restriction inhibits mTORC1 signaling through both upstream pathways of mTORC that converge on the lysosome. Autophagy is the major degradation pathway...
- gonadal hormones underlie male-specific improvements in glucose tolerance and mTORC 2 signaling". Aging Cell. 16 (6): 1256–1266. doi:10.1111/acel.12656. ISSN 1474-9718...
- inhibitor) and everolimus (mTORC inhibitor) for the treatment of NF1 plexiform neurofibromas, sirolimus (rapamycin) (mTORC inhibitor) for MPNSTs, or lovastatin...
- and prostate cancer cell lines and tissues. Knockdown of mLST8 prevented mTORC formation and inhibited tumor growth and invasiveness. GRCh38: Ensembl release...
- oncoprotein caused an upregulation of mTORC1 (Sanden et al., 2013). Thus, a mTORC inhibitor could be a potential treatment. "Acute Myeloid Leukemia - Signs...
- affect expression of NFE2L1 through a mTORC and SREBP-1 mediated pathway. Growth factors induce higher activity of mTORC, which then promotes activity of its...