-
required by
other MAPKs for
substrate binding.
These are
usually referred to as "atypical"
MAPKs. It is yet
unclear if the
atypical MAPKs form a
single group...
- kinase. In a
technical sense, RAF, MEK, and
MAPK are all mitogen-activated kinases, as is MNK (see below).
MAPKs were
originally called "extracellular signal-regulated...
-
activation of
MAPKs, and gene
responses that are
similar to each other.
Although there appears to be an
important relationship between MAPKs with EF-Tu-triggered...
- (DUSPs)
because they
deactivate MAPK by
dephosphorylating the
Threonine and the
Tyrosine residues residing in
MAPKs activation site. MKPs have a catalytic...
- dual-specificity
kinase enzyme which phosphorylates mitogen-activated
protein kinase (
MAPK). MAP2K is
classified as EC 2.7.12.2.
There are
seven genes: MAP2K1 (a.k...
- mitogen-activated
protein kinases are a
class of mitogen-activated
protein kinases (
MAPKs) that are
responsive to
stress stimuli, such as cytokines,
ultraviolet irradiation...
- and/or MEK2. They can be used to
affect the
MAPK/ERK
pathway which is
often overactive in some cancers. (See
MAPK/ERK pathway#Clinical significance.) Hence...
- have been
developed as
treatments for some
types of cancer. MAP
kinases (
MAPKs) are a
family of serine/threonine
kinases that
respond to a
variety of extracellular...
- off infection). This
regulation of
cytokines appears to
occur via the p38
MAPKs (mitogen-activated
protein kinase)-dependent pathway. Usually, the p38 within...
-
Aaron (3
February 2016). "Axon self destruction: new
links among SARM1,
MAPKs, and NAD+ metabolism". Neuron. 89 (3): 449–460. doi:10.1016/j.neuron.2015...
