-
required by
other MAPKs for
substrate binding.
These are
usually referred to as "atypical"
MAPKs. It is yet
unclear if the
atypical MAPKs form a
single group...
- kinase. In a
technical sense, RAF, MEK, and
MAPK are all mitogen-activated kinases, as is MNK (see below).
MAPKs were
originally called "extracellular signal-regulated...
-
activation of
MAPKs, and gene
responses that are
similar to each other.
Although there appears to be an
important relationship between MAPKs with EF-Tu-triggered...
- p38α mitogen-activated
protein kinase (
MAPK)
which is the
prototypic member of the p38
MAPK family. p38
MAPKs are also
known as stress-activated...
- mitogen-activated
protein kinases are a
class of mitogen-activated
protein kinases (
MAPKs) that are
responsive to
stress stimuli, such as cytokines,
ultraviolet irradiation...
- dual-specificity
kinase enzyme which phosphorylates mitogen-activated
protein kinase (
MAPK). MAP2K is
classified as EC 2.7.12.2.
There are
seven genes: MAP2K1 (a.k...
- (DUSPs)
because they
deactivate MAPK by
dephosphorylating the
Threonine and the
Tyrosine residues residing in
MAPKs activation site. MKPs have a catalytic...
- then
activates a
specific MAPK.
While the ERK
MAPKs are
activated by
mitogenic stimulation, the CSBP2 (p38α) and JNK
MAPKs are
activated by environmental...
- C,
Abdelmohsen K,
Gorospe M (2020). "Regulation of
senescence traits by
MAPKs". GeroScience. 42 (2): 397–408. doi:10.1007/s11357-020-00183-3. PMC 7205942...
- have been
developed as
treatments for some
types of cancer. MAP
kinases (
MAPKs) are a
family of serine/threonine
kinases that
respond to a
variety of extracellular...