- Mitogen-activated
protein kinase kinase (also
known as MAP2K, MEK,
MAPKK) is a dual-specificity
kinase enzyme which phosphorylates mitogen-activated protein...
- A mitogen-activated
protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific
protein kinases involved in
directing cellular responses...
- Pore-forming
proteins (PFTs, also
known as pore-forming toxins) are
usually produced by bacteria, and
include a
number of
protein exotoxins but may also...
- Ras
activates Raf
kinase (also
known as MAPKKK),
which activates MEK (
MAPKK). MEK
activates MAPK (also
known as ERK),
which can go on to
regulate transcription...
- Some
kinases have dual-specificity
kinase activities. For example, MEK (
MAPKK),
which is
involved in the MAP
kinase cascade, is a both a serine/threonine...
-
Activated Raf
stimulates MAPK-kinase (
MAPKK or MEK) by
phosphorylating a
serine residue in its
activation loop.
MAPKK then
phosphorylates MAPK (ERK1/2) on...
- The
cascade includes MAPKKK,
MAPKK, and MAPK. Each is dual
phosphorylated by the other,
MAPKKK dual
phosphorylates MAPKK and in turn dual phosphorylates...
- 1954 by
Burnett and Kennedy. EC 2.7.11.1 Mos/Raf
kinases form part of the
MAPKK Kinase family and are
activated by
growth factors. The
enzyme functions...
-
kinase related to the dual
specific mitogen-activated
protein kinase kinase (
MAPKK) family.
Evidence suggests that
mitotic phosphorylation is
required for...
-
which produces a
metalloprotease lethal factor (LF)
protein to
target MAPKK, is
vulnerable to
human neutrophil protein-1 (HNP-1). This
group showed...
