- Mitogen-activated
protein kinase kinase (also
known as MAP2K, MEK,
MAPKK) is a dual-specificity
kinase enzyme which phosphorylates mitogen-activated protein...
- A mitogen-activated
protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific
protein kinases involved in
directing cellular responses...
- Pore-forming
proteins (PFTs, also
known as pore-forming toxins) are
usually produced by bacteria, and
include a
number of
protein exotoxins but may also...
- Ras
activates Raf
kinase (also
known as MAPKKK),
which activates MEK (
MAPKK). MEK
activates MAPK (also
known as ERK),
which can go on to
regulate transcription...
-
elements include the MOS protein, mitogen-activated
protein kinase kinase (
MAPKK/MEK1), and MAPK. The
protein kinase p90 (RSK) is one
critical target of...
- (MKK6) and SERK1 (MKK4),
MAPKKs that
activate CSBP2 (p38α) and JNK,
respectively but
cannot phosphorylate PRKMK1 (MKK1), an
MAPKK that
activates ERKs. MEKK4...
- MAP
kinase kinase 6 (
MAPKK 6) or MAPK/ERK
kinase 6 is an
enzyme that in
humans is
encoded by the MAP2K6 gene, on
chromosome 17.
MAPKK 6 is a
member of the...
- Some
kinases have dual-specificity
kinase activities. For example, MEK (
MAPKK),
which is
involved in the MAP
kinase cascade, is a both a serine/threonine...
- 1954 by
Burnett and Kennedy. EC 2.7.11.1 Mos/Raf
kinases form part of the
MAPKK Kinase family and are
activated by
growth factors. The
enzyme functions...
- by
catalytically unlocking this
particular kinase for
activation by its
MAPKK Ste7.
Scaffolds localize the
signaling reaction to a
specific area in the...
