- Mitogen-activated
protein kinase kinase (also
known as MAP2K, MEK,
MAPKK) is a dual-specificity
kinase enzyme which phosphorylates mitogen-activated protein...
- A mitogen-activated
protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific
protein kinases involved in
directing cellular responses...
- Pore-forming
proteins (PFTs, also
known as pore-forming toxins) are
usually produced by bacteria, and
include a
number of
protein exotoxins but may also...
- Ras
activates Raf
kinase (also
known as MAPKKK),
which activates MEK (
MAPKK). MEK
activates MAPK (also
known as ERK),
which can go on to
regulate transcription...
-
elements include the MOS protein, mitogen-activated
protein kinase kinase (
MAPKK/MEK1), and MAPK. The
protein kinase p90 (RSK) is one
critical target of...
-
kinases Raf a MAP
Kinase Kinase Kinase (MAPKKK), MEK a MAP
Kinase Kinase (
MAPKK), and ERK a MAP Kinase(MAPK),
which in turn
regulate genes that mediate...
- Some
kinases have dual-specificity
kinase activities. For example, MEK (
MAPKK),
which is
involved in the MAP
kinase cascade, is a both a serine/threonine...
- its
biological functions through binding to
signalling proteins of the
MAPKK level of the MAPK pathway,
therefore eliciting a
regulatory role in the...
-
Activated Raf
stimulates MAPK-kinase (
MAPKK or MEK) by
phosphorylating a
serine residue in its
activation loop.
MAPKK then
phosphorylates MAPK (ERK1/2) on...
- by
catalytically unlocking this
particular kinase for
activation by its
MAPKK Ste7.
Scaffolds localize the
signaling reaction to a
specific area in the...
