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Proteoglycan 4 or
lubricin is a
proteoglycan that in
humans is
encoded by the PRG4 gene. It acts as a joint/boundary lubricant.
Lubricin is
present in synovial...
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hyaluronan secreted by fibroblast-like
cells in the
synovial membrane,
lubricin (proteoglycan 4; PRG4)
secreted by the
surface chondrocytes of the articular...
- can
entirely wear down cartilage,
causing direct bone-to-bone contact.
Lubricin, a
glycoprotein abundant in
cartilage and
synovial fluid,
plays a major...
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synovial fluid "ropy"-like egg-white,
together with a
molecule called lubricin,
which lubricates the
joint surfaces. The
water of
synovial fluid is not...
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fluid and was
found to
increase the
viscosity of the fluid.
Along with
lubricin, it is one of the fluid's main
lubricating components.
Hyaluronic acid...
- 1186/s12891-020-3094-y. PMC 7006114. PMID 32028937. Sun YL, et al. (2015). "
Lubricin in
Human Achilles Tendon: The
Evidence of
Intratendinous Sliding Motion...
- as a
lubricant for the
cartilage surfaces. This gene is also
known as
lubricin. This
condition was
first described in 1986. and is a
syndrome of camptodactyly...
-
Complete Detectable O-Glycan
Repertoire of the
Candidate Therapeutic,
Lubricin".
Analytical Chemistry. 91 (15): 9819–9827. doi:10.1021/acs.analchem.9b01485...
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normally absent in
other fibroblast lineages.
These include especially lubricin, a
protein crucial for the
joint lubrication. Furthermore,
these cells...
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small amounts that help
maintain structure and organization. Specifically,
lubricin helps to
create a
lubricating surface on the
cartilage for
easier joint...
