-
reaction of
lipoic acid biosynthesis, is impaired. The
result is a
reduced lipoylation degree of
important mitochondrial enzymes, such as
pyruvate dehydrogenase...
-
attached to
specific lysine residues on
target enzymes in a
process called lipoylation. This post‑translational
modification is
essential for the
activity of...
- deficiency,
glycolysis is
reduced by -50%,
which is
caused by
reduced lipoylation of
mitochondrial enzymes such as the
pyruvate dehydrogenase complex and...
- (GPI)
anchor formation via an
amide bond to C-terminal tail
lipoylation (a type of acylation),
attachment of a
lipoate (C8)
functional group...
-
precursor reaction of
lipoic acid biosynthesis. The
result is a
reduced lipoylation degree of
important mitochondrial enzymes, such as
oxoglutarate dehydrogenase...
- (Cronan, 2001). In conclusion, the
thumb functions to
inhibit the
aberrant lipoylation of the
target lysine by
lipoyl protein ligase (Reche and Perham, 1999)...
-
partially redundant role in
lipoic acid
synthesis and thus in
protein lipoylation by
providing malonyl-CoA for
mitochondrial fatty acid
synthesis (mtFASII)...
- glycosylation, glycylation, hydroxylation, isoprenylation, lactylation,
lipoylation, methylation, nitroalkylation, phosphopantetheinylation, phosphorylation...
- RNA
phosphodiester bond hydrolysis,
endonucleolytic tRNA
processing protein lipoylation tRNA 5'-leader
removal rRNA
processing Sources:Amigo / QuickGO...
- Bagby, Stefan; Hough,
David W.; Danson,
Michael J. (2009). "A
unique lipoylation system in the Archaea". FEBS Journal. 276 (15): 4012–4022. doi:10.1111/j...
