- Initially, two
lipoxins were identified,
lipoxin A4 (LXA4) and LXB4, but more
recent studies have
identified epimers of
these two LXs: the epi-
lipoxins, 15-epi-LXA4...
-
detailed at the
lipoxin site.
Lipoxins Specialized pro-resolving
mediators Serhan CN (2001). "
Lipoxins and aspirin-triggered 15-epi-
lipoxins are endogenous...
- HxB3.
Lipoxins (Lx)
include the
following metabolites of
arachidonic acid: LxA4 and LxB4 (see
Specialized pro-resolving mediators). Epi-
lipoxins (epi-Lx)...
-
Romano M,
Cianci E,
Simiele F,
Recchiuti A (Aug 2015). "
Lipoxins and aspirin-triggered
lipoxins in
resolution of inflammation". Eur J Pharmacol. 760: 49–63...
- 15(R)-HETE
which product can be
further metabolized to epi-
lipoxins. The
lipoxins and epi-
lipoxins are
potent anti-inflammatory
agents and may contribute...
- Aspirin-modified COX-2
produces 15-epi-
lipoxins,
which act to
resolve inflammatory responses similar to
other lipoxins.
Newer NSAID drugs called COX-2 selective...
- 15S-hydroperoxy-eicosatetraenoic acid. The two aspirin-triggered
lipoxins (AT-
lipoxins) or epi-
lipoxins differ structurally from LxA4 and LxB4 only in the S versus...
- and derivatives,
including prostaglandins, leukotrienes, thromboxanes,
lipoxins, and others. Only two
fatty acids are
known to be
essential for humans:...
- pro-inflammatory eicosanoids. Anti-inflammatory
eicosanoids include lipoxins, epi-
lipoxins, and resolvins,
which cause release of
growth hormones.[citation...
-
Production of anti-inflammatory
specialized proresolving mediators, i.e.
lipoxins, resolvins, maresins, and
neuroprotectins Downregulation of pro-inflammatory...
