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Lipophilicity (from Gr**** λίπος "fat" and φίλος "friendly") is the
ability of a
chemical compound to
dissolve in fats, oils, lipids, and non-polar solvents...
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Lipophilic efficiency (LiPE),
sometimes referred to as ligand-
lipophilicity efficiency (LLE) is a
parameter used in drug
design and drug
discovery to...
- The hydrophilic–
lipophilic balance (HLB) of a
surfactant is a
measure of its
degree of
hydrophilicity or
lipophilicity,
determined by
calculating percentages...
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Lipophilic bacteria (fat-loving bacteria) are
bacteria that may
proliferate in lipids. They
include lipophilic corynebacteria.
Cutibacterium acnes is a...
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Agents organized by
lipid solubility (
lipophilicity) High
lipophilicity: propranolol,
labetalol Intermediate lipophilicity: metoprolol, bisoprolol, carvedilol...
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partition ratio. Kow
serves as a
measure of the
relationship between lipophilicity (fat solubility) and
hydrophilicity (water solubility) of a substance...
- cholesterol.
Lipophilicity of the
statins is
considered to be
quite important since the
hepatoselectivity of the
statins is
related to
their lipophilicity. The...
- the log P
value is a
measure of
lipophilicity or hydrophobicity.: 275ff : 6 The
defined precedent is for the
lipophilic and
hydrophilic phase types to...
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chemical compound possessing both
hydrophilic (water-loving, polar) and
lipophilic (fat-loving, nonpolar) properties. Such a
compound is
called amphiphilic...
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predicted to have good oral bioavailability.
During drug discovery,
lipophilicity and
molecular weight are
often increased in
order to
improve the affinity...
