-
Lipoxygenases (EC 1.13.11.-) (LOX) are a
family of (non-heme) iron-containing enzymes, more
specifically oxidative enzymes, most of
which catalyze the...
- The oil of the seed has been
confirmed to
possess anti-oxidant, anti-
lipooxygenase and
antimicrobial (against
various microbe strains) activities, among...
- effects.
Unlike other NSAIDs, it does not
inhibit cyclooxygenase or
lipooxygenase, and is not ulcerogenic. It is
described as
having powerful reinforcing...
-
modulating the
inflammatory response derived from the
cyclooxygenase and
lipooxygenase pathways. It
appears to act
locally on
colonic mucosa.
Mesalazine is...
-
considered disagreeable by most Westerners. This is
caused by the
lipooxygenase (LOX) in the soy
oxidizing the fat in the beans.
Rehydrating the beans...
- risk of hepatotoxicity)
Clonixin Licofelone acts by
inhibiting LOX (
lipooxygenase) and COX and
hence known as 5-LOX/COX
inhibitor H-harpagide in figwort...
- of
Pharmacokinetics and
Safety of
Utreloxastat (PTC857), a
Novel 15-
Lipooxygenase Inhibitor for the
Treatment of
Amyotrophic Lateral Sclerosis". Clinical...
-
substrate is
released from the cell
membrane phospholipid will
enter the
lipooxygenase pathway to
produce leukotriene A4. In this pathway,
arachidonic acid...
-
dioxygenation of
polyunsaturated fatty acids in this case, α-linolenic acid.
Lipooxygenase specifically binds to
polyunsaturated fatty acids that have a cis,cis-1...
-
functions as a
membrane anchor for 5-
lipooxygenase and as an
amine acid-bind protein. How FLAP
activates 5-
lipooxygenase is not
completely understood, but...