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Lipoic acid (LA), also
known as α-
lipoic acid, alpha-
lipoic acid (ALA) and
thioctic acid, is an
organosulfur compound derived from
caprylic acid (octanoic...
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Dihydrolipoic acid is an
organic compound that is the
reduced form of
lipoic acid. This
carboxylic acid
features a pair of
thiol groups, and therefore...
- pilocarpine, zinc supplementation,
alterations in drug therapy, and
alpha lipoic acid. The
alterations in the
sense of taste,
usually a
metallic taste, and...
-
peroxide consumption via glutaredoxin.
Glutathionylation "protects" the
lipoic acid of the E2
domain from
undergoing oxidative damage,
which helps spare...
-
trivial name for 6,8-dithiooctanoic amide. It is the
functional form of
lipoic acid, i.e the
carboxyl group is
attached to
protein via an
amine with an...
-
February 2017, an
article was
published in
Nature Medicine entitled "Alpha
lipoic acid
treatment prevents cystine urolithiasis in a
mouse model of cystinuria"...
- lipoyl-protein:protein N-lipoyltransferases. The
metabolism of the
cofactors Biotin and
lipoic acid
share this family. They also
share the
target modification domain (Pfam...
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parent molecule is not
important but
substituted derivatives,
especially lipoic acid and its derivatives, are important.
Several occur in foods. 1,2-Dithiolane...
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corresponding substrates. This
particular enzyme parti****tes in the
final step of
lipoic acid metabolism,
transferring two
sulfur atoms from its 4Fe-4S
cluster onto...
-
candidates in
trials include vasodilators, corticosteroids,
immune therapies,
lipoic acid, bevacizumab, and
recombinant angiotensin-converting
enzyme 2. In March...
