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Illustrative of the
biochemical role of
lipoamide is in the
conversion of
pyruvate to
acetyl lipoamide.
Lipoamide is
found in a
large number of
plant and...
-
dehydrogenase is an
enzyme that
catalyzes the
reaction of
pyruvate and a
lipoamide to give the
acetylated dihydrolipoamide and
carbon dioxide. The conversion...
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unable to
cleave the
lipoic acid-L-lysine
amide bond. Both
synthetic lipoamide and (R)-lipoyl-L-lysine are
rapidly cleaved by
serum lipoamidases, which...
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metal ion:
loosely bound thiamine pyrophosphate (TPP),
covalently bound lipoamide and
flavin adenine dinucleotide (FAD),
cosubstrates nicotinamide adenine...
- gene. DLD is a
flavoprotein enzyme that
oxidizes dihydrolipoamide to
lipoamide.
Dihydrolipoamide dehydrogenase (DLD) is a
mitochondrial enzyme that plays...
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dihydrolipoamide dehydrogenase (E3), six cofactors:
thiamine pyrophosphate (TPP),
lipoamide,
coenzyme A (CoA),
flavin adenine dinucleotide (FAD),
magnesium ion, and...
- 5
steps that this
complex carries out:
thiamine pyrophosphate (TPP),
lipoamide, and
coenzyme A. This step is only one of the
central metabolic pathway...
- The branched-chain α-ketoacid
dehydrogenase complex (BCKDC or
BCKDH complex) is a multi-subunit
complex of
enzymes that is
found on the
mitochondrial inner...
- [3-methyl-2-oxobutanoate
dehydrogenase (
lipoamide)]-phosphatase, [3-methyl-2-oxobutanoate
dehydrogenase (
lipoamide)]-phosphate phosphohydrolase) is an enzyme...
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Pyruvate dehydrogenase lipoamide kinase isozyme 1,
mitochondrial is an
enzyme that in
humans is
encoded by the PDK1 gene. It
codes for an
isozyme of pyruvate...