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Leptin (from Gr**** λεπτός leptos, "thin" or "light" or "small"), also
known as
obese protein, is a
protein hormone predominantly made by
adipocytes (cells...
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Leptin receptor, also
known as LEP-R or OB-R, is a type I
cytokine receptor, a
protein that in
humans is
encoded by the LEPR gene. LEP-R
functions as a...
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recognized as a
major endocrine organ, as it
produces hormones such as
leptin, estrogen, resistin, and
cytokines (especially TNFα). In obesity, adipose...
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Maria Leptin (born 15
September 1954) is a
German developmental biologist and immunologist, and the
current president of the
European Research Council...
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Investigator of the
Howard Hughes Medical Institute. His
discovery of the
hormone leptin and its role in
regulating body
weight has had a
major role in the area...
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environmental risk factors.
Monogenetic obesity mostly affects the
hypothalamus and
leptin–melanocortin
system (see
hypothalamic obesity). However, it
accounts for...
- the discovery, in 1994, of
leptin, a
hormone produced by the
adipose tissue that
appeared to
provide negative feedback.
Leptin is a
peptide hormone that...
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Leptin might be the
cause of the GnRH rise.
Leptin has
receptors in the
hypothalamus which synthesizes GnRH.
Individuals who are
deficient in
leptin fail...
- the face). This
condition is also
characterized by a lack of
circulating leptin which may lead to osteosclerosis. The
absence of fat
tissue is ****ociated...
-
excessively due to
mutations in the gene
responsible for the
production of
leptin and
becomes profoundly obese. It is an
animal model of type II diabetes...
