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Leptin (from Gr**** λεπτός leptos, "thin" or "light" or "small"), also
known as
obese protein, is a
protein hormone predominantly made by
adipocytes (cells...
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Leptin receptor, also
known as LEP-R or OB-R, is a type I
cytokine receptor, a
protein that in
humans is
encoded by the LEPR gene. LEP-R
functions as a...
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recognized as a
major endocrine organ, as it
produces hormones such as
leptin, estrogen, resistin, and
cytokines (especially TNFα). In obesity, adipose...
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Maria Leptin (born 1954) is a
German developmental biologist and immunologist, and the
current president of the
European Research Council. She was the...
- to the
discovery of
leptin, she
analyzed leptin concentrations of the mice in the
parabiotic experiments.
After injecting leptin into each pair's obese...
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Leptin might be the
cause of the GnRH rise.
Leptin has
receptors in the
hypothalamus which synthesizes GnRH.
Individuals who are
deficient in
leptin fail...
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environmental risk factors.
Monogenetic obesity mostly affects the
hypothalamus and
leptin–melanocortin
system (see
hypothalamic obesity). However, it
accounts for...
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Investigator of the
Howard Hughes Medical Institute. His
discovery of the
hormone leptin and its role in
regulating body
weight has had a
major role in the area...
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Teleost leptins are a
family of
peptide hormones found in fish (teleostei) that are
orthologs of the
mammalian hormone leptin. The
teleost and mammalian...
- the face). This
condition is also
characterized by a lack of
circulating leptin which may lead to osteosclerosis. The
absence of fat
tissue is ****ociated...
