- The
latrunculins are a
family of
natural products and
toxins produced by
certain sponges,
including genus Latrunculia and Negombata,
whence the name is...
-
these drugs have
multiple effects on the cytoskeleton: for example,
Latrunculin both
prevents actin polymerization as well as
enhancing its rate of depolymerization...
- (28 in).
Negombata magnifica is
extremely toxic because of the
toxin latrunculin.
Negombata magnifica lives on
shallow coral reefs in the
northern waters...
-
maintenance of cell
polarity revealed using the
actin inhibitor latrunculin-A
Latrunculin alters the actin-monomer
subunit interface to
prevent polymerization...
-
dynamics are
widely used in
research to
study actin's role in biology.
Latrunculin – a
toxin produced by
sponges –
binds to G-actin
preventing it from joining...
- "Total
Syntheses of the Actin-Binding
Macrolides Latrunculin A, B, C, M, S and 16-epi-
Latrunculin B". Chem. Eur. J. 13 (1): 115–134. doi:10.1002/chem...
- x. PMID 19686371.
Gibbon BC,
Kovar DR,
Staiger CJ (December 1999). "
Latrunculin B has
different effects on
pollen germination and tube growth". The Plant...
- 1021/jo00019a004.
James D. White,
Motoji Kawasaki: "Total
synthesis of (+)-
latrunculin A", in: J. Am. Chem. Soc., 1990, 112, pp. 4991–4993; doi:10.1021/ja00168a071...
-
RABBIT MUSCLE ALPHA-ACTIN:
HUMAN GELSOLIN DOMAIN 1 1esv:
COMPLEX BETWEEN LATRUNCULIN A:RABBIT
MUSCLE ALPHA ACTIN:HUMAN
GELSOLIN DOMAIN 1 1h1v:
GELSOLIN G4-G6/ACTIN...
- 1021/jo0610053
Diverted total synthesis:
Preparation of a
focused library of
latrunculin analogues and
evaluation of
their actin-binding
properties Alois Fürstner...
