- Beta-
lactamases (β-
lactamases) are
enzymes (EC 3.5.2.6)
produced by
bacteria that
provide multi-resistance to beta-lactam
antibiotics such as penicillins...
- Beta-
lactamases are a
family of
enzymes involved in
bacterial resistance to beta-lactam antibiotics. In
bacterial resistance to beta-lactam antibiotics...
- gene for NDM-1 is one
member of a
large gene
family that
encodes beta-
lactamase enzymes called carbap****ses.
Bacteria that
produce carbap****ses are...
-
synthesizing a β-
lactamase, an
enzyme that
attacks the β-lactam ring. To
overcome this resistance, β-lactam
antibiotics can be
given with β-
lactamase inhibitors...
- beta-
lactamases. Most beta-
lactamases identified in Bacteroides, Prevotella, and
Capnocytophaga belong to the
Ambler class A.
Several beta-
lactamases encoded...
- of amoxicillin, a β-lactam antibiotic, and pot****ium clavulanate, a β-
lactamase inhibitor. It is
specifically used for
otitis media,
streptococcal pharyngitis...
- tazobactam, β-
lactamase inhibitors,
alongside penicillin gives penicillin activity against β-
lactamase-producing bacteria. β-
Lactamase inhibitors irreversibly...
-
Staphylococcus aureus (beta-
lactamase and non-beta-
lactamase producing),
Staphylococcus epidermidis (beta-
lactamase and non-beta-
lactamase producing), Staphylococcus...
-
inactivated by β-
lactamases.[citation needed]
Flucloxacillin was
developed in the 1960s
following an
increase in penicillin-resistant (beta-
lactamase producing)...
-
Clavulanic acid is a β-lactam drug that
functions as a mechanism-based β-
lactamase inhibitor.
While not
effective by
itself as an antibiotic, when combined...