-
Kynurenic acid (KYNA or KYN) is a
product of the
normal metabolism of
amino acid L-tryptophan. It has been
shown that
kynurenic acid
possesses neuroactive...
-
Metabolites involved in the
kynurenine pathway include tryptophan, kynurenine,
kynurenic acid,
xanthurenic acid,
quinolinic acid, and 3-hydroxykynurenine. The...
-
levels of
another NMDA antagonist,
kynurenic acid, may
aggravate the
symptoms of schizophrenia,
according to the "
kynurenic hypothesis". NMDA
receptor antagonists...
-
derivative of
kynurenic acid and has
similarly been
found to
antagonize AMPA and NMDA, as well as
their corresponding receptors.
Kynurenic acid van B****...
- riluzole, memantine,
methoxetamine (MXE),
methoxphenidine (MXP) and
kynurenic acid.
While dizocilpine is
generally considered to be the prototypical...
- the
glycine site of the NMDA
receptor complex. 7-Chlorokynurenic acid
Kynurenic acid
McNamara D,
Smith EC,
Calligaro DO, O'Malley PJ,
McQuaid LA, Dingledine...
- (benzohexonium)
Hydroxybupropion Hydroxynorketamine Ibogaine Isoflurane Ketamine Kynurenic acid
Laudanosine Laudexium (laudolissin)
Levacetylmethadol Levomethadone...
- 5-Fluorowillardiine,
Domoic acid,
Quisqualic acid, etc. Antagonists: CNQX,
Kynurenic acid, NBQX, Perampanel, Piracetam, etc.
Positive allosteric modulators:...
-
Caroverine CNQX
Dasolampanel DNQX
Fanapanel (MPQX) GAMS
Kaitocephalin Kynurenic acid
Kynurenine Licostinel (ACEA-1021) NBQX PNQX
Selurampanel Tezampanel...
- Some
endogenous antagonists and
inverse agonists are also
known (e.g.,
kynurenic acid at the NMDA receptor), but
these are much less common.
Goodman and...
