-
Kininogens are
precursor proteins for kinins,
biologically active polypeptides involved in
blood coagulation, vasodilation,
smooth muscle contraction,...
- High-molecular-weight
kininogen (HMWK or HK) is a
circulating plasma protein which parti****tes in the
initiation of
blood coagulation, and in the generation...
-
Scharfstein J,
Schmitz V, Svensjö E,
Granato A,
Monteiro AC (2007). "
Kininogens coordinate adaptive immunity through the
proteolytic release of bradykinin...
- (2004). "Primary
structures of
guinea pig high- and low-molecular-weight
kininogens". Int Immunopharmacol. 4 (10–11): 1391–400. doi:10.1016/j.intimp.2004...
-
component of the kinin-kallikrein system.
Their precursors are
kininogens.
Kininogens contain a 9-11
amino acid
bradykinin sequence. In botany, the plant...
- kallikrein) are
serine proteases that
liberate kinins (BK and KD) from the
kininogens,
which are
plasma proteins that are
converted into
vasoactive peptides...
-
formation of the
primary complex on
collagen by high-molecular-weight
kininogen (HMWK), prekallikrein, and FXII (Hageman factor).
Prekallikrein is converted...
-
Plasma kallikrein liberates kinins (bradykinin and kallidin) from the
kininogens,
peptides responsible for the
regulation of
blood pressure and activation...
- 2004). "Primary
structures of
guinea pig high- and low-molecular-weight
kininogens".
International Immunopharmacology. 4 (10–11): 1391–400. doi:10.1016/j...
- with
mutations in
genes for
Factor XII,
angiopoietin 1,
plasminogen or
kininogen 1. The
pathophysiologic mechanisms contributing to
bradykinin mediated...
