- two main
types of
kininogen (KNG), high-molecular-weight-
kininogen and low-molecular-weight-
kininogen, with a
third type – T-
kininogen – only
found in rats...
- High-molecular-weight
kininogen (HMWK or HK) is a
circulating plasma protein which parti****tes in the
initiation of
blood coagulation, and in the generation...
-
encoded by the KNG1 gene.
Kininogen-1 is the
precursor protein to high-molecular-weight
kininogen (HMWK), low-molecular-weight
kininogen (LMWK), and bradykinin...
- of some Arg- and Lys- bonds,
including Lys-Arg and Arg-Ser in (human)
kininogen to
release bradykinin Plasma kallikrein and its
precursor are encoded...
- compounds.[citation needed] High-molecular
weight kininogen (HMWK) and low-molecular
weight kininogen (LMWK) are
precursors of the polypeptides. They have...
- Kallikrein, an
enzyme that
proteolytically cleaves high-molecular-weight
kininogen to
produce bradykinin; it is
secreted by the
acinar cells of all three...
-
formation of the
primary complex on
collagen by high-molecular-weight
kininogen (HMWK), prekallikrein, and FXII (Hageman factor).
Prekallikrein is converted...
- with
mutations in
genes for
Factor XII,
angiopoietin 1,
plasminogen or
kininogen 1. The
pathophysiologic mechanisms contributing to
bradykinin mediated...
- an 85,000 Mr
serine protease that
complexes with high-molecular-weight
kininogen. PK is the
precursor of
plasma kallikrein,
which is a
serine protease...
-
makes bradykinin by
proteolytic cleavage of its
kininogen precursor, high-molecular-weight
kininogen (HMWK or HK), by the
enzyme kallikrein. Moreover...
