Definition of Ketoreduction. Meaning of Ketoreduction. Synonyms of Ketoreduction
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Definition of Ketoreduction
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- by ketoreduction (KR) and dehydration. Modulethree adds a malonyl-CoA extender unit, followed by SAM-dependent methylation at C8, ketoreduction, and... - via CYP3A4 O-Demethylation to oxymorphonepredominantly via CYP2D6 6-Ketoreduction to 6α- and 6β-oxycodol N-Oxidation to oxycodone-N-oxide In humans, N-demethylation... - -Adenylation1 (A1) -Thiolation1 (T1) -Condensation2 (C2) -Adenylation2 (A2) -Ketoreduction (KR) -Thiolation2 (T2). The A1 domainactivates and loads threonine... - ketoreductase (KR) domains. Type A and B KRs refer to the two directions of ketoreduction that are correlated with specificaminoacids in the active site. Four...