- 17β-Hydroxysteroid
dehydrogenases (17β-HSD, HSD17B) (EC 1.1.1.51), also 17-ketosteroid
reductases (17-KSR), are a
group of
alcohol oxidoreductases which...
- DH=dehydratase, ER=enoyl reductase, HMG=3-hydroxy-3-methylglutaric acid, MeT=methyl transferase, KR=
ketoreductase, KS=ketosynthase, TE=thioesterase....
- reductase, PGE-9-
ketoreductase, PGE2 9-oxoreductase, PGE2 reductase-9-
ketoreductase,
prostaglandin 9-
ketoreductase,
prostaglandin E 9-
ketoreductase, and prostaglandin...
-
furan ring
formation between C6 and C8. AveF has NAD(P)H-dependent
ketoreductase activity which reduces the C5 keto
group to a hydroxyl. AveC influences...
-
protein (ACP) site, and
acyltransferase (AT), but may also
contain a
Ketoreductase (KR),
Dehydrotase (DH), and Enol
Reductase (ER) for
additional reduction...
- dehydrogenase, AT-acyltransferase, DH-dehydratase, KS-ketoacyl synthase, KR-
ketoreductase, MT-methyltransferase, ER-enoylreductase, C-condensation, TE-thioesterase...
-
combinations of
domains that
reduce the
carbonyl group to a
hydroxyl (via a
ketoreductase), an
olefin (via a dehydratase), or a
methylene (via an enoylreductase)...
-
development due to 17-beta-hydroxysteroid
dehydrogenase 3 deficiency, 17-
ketoreductase deficiency, 17-ketosteroidreductase deficiency.
Biochemical effects...
-
Tailoring enzymes of type I PKS that can be
involved in each
module are
ketoreductase (KR),
dehydratase (DH), and
enoyl reductase (ER). Once
polyketide has...
-
reduced to the
fully saturated carbon chain by the
sequential action of a
ketoreductase (KR),
dehydratase (DH), and
enoyl reductase (ER). The
growing fatty...
