- context, is
usually encountered as its
conjugate base
ketoisovalerate, (CH3)2CHC(O)CO2−. α-
Ketoisovalerate undergoes hydroxymethylation to give ketopantoate:...
- (vitamin B5), a
component of
coenzyme A. Its
biosynthesis proceeds from
ketoisovalerate by hydroxymethylation: (CH3)2CHC(O)CO2− + CH2O → HOCH2(CH3)2CC(O)CO2−...
-
initial part of the
pathway also
leads to leucine. The
intermediate α-
ketoisovalerate undergoes reductive amination with glutamate.
Enzymes involved in this...
- a glutamate-alanine transaminase, and 2)
conversion of
valine to α-
ketoisovalerate via
Transaminase C. Not much is
known about the
regulation of alanine...
-
their deaminated derivatives (L-alpha-keto-beta-methylvalerate, alpha-
ketoisovalerate, and alpha-ketoisocaproate, respectively) and
converting them to α-Methylbutyryl-CoA...
-
other organisms has been
genetically modified to
produce isobutanol. α-
Ketoisovalerate,
derived from
oxidative deamination of valine, is
prone to decarboxylation...
-
amino acid
biosynthetic pathway is
shifted to
alcohol production. α-
Ketoisovalerate,
derived from valine, is
prone to
decarboxylation to give isobutyraldehyde...
- isoleucine-derived α-keto-β-methylvaleric acid,
followed by α-ketoisocaproate and α-
ketoisovalerate. The enzyme's high
affinity toward branched-chain α-keto
acids allows...
- The
amino group of
valine is
replaced by a keto-moiety to
yield α-
ketoisovalerate, which, in turn,
forms α-ketopantoate
following transfer of a methyl...
- the
hyperforin core structure. Isobutryl-CoA is
derived from an a-
ketoisovalerate intermediate (15). The
bicyclic structure suggests that it has elements...
