- In
organic chemistry, keto
acids or
ketoacids (also
called oxo
acids or oxoacids) are
organic compounds that
contain a
carboxylic acid
group (−COOH) and...
-
decarboxylation of branched, short-chain alpha-
ketoacids.
BCKDC is a
member of the
mitochondrial α-
ketoacid dehydrogenase complex family,
which also includes...
-
generally caused when the body
produces an
excess amount of
organic acids (
ketoacids in ketoacidosis, or
lactic acid in
lactic acidosis). A
state of chronic...
-
aminotransferase (BCAT) into
their relevant α-
ketoacids. The
second step
involves the
conversion of α-
ketoacids into acetoacetate, acetyl-CoA, and succinyl-CoA...
- conditions,
excessive free
fatty acid
metabolism results in the
production of
ketoacids,
acetoacetic acid, and beta-hydroxybutyrate.
Lactic acidosis results from...
- acetyl-CoA.
Thiamine (T:) is the
active component for
decarboxylation of alpha-
ketoacids,
including pyruvate: T: + RC(O)CO2H → T=C(OH)R + CO2 T=C(OH)R + R'COOH...
-
importance of the
ketoacid side chain, but it is well
known that
pyoverdine molecules with
different ketoacids (congeners) co-exist.
Ketoacids that have been...
- are
converted to α-
ketoacids by
transamination and
eventually to isovaleryl-CoA
through oxidative decarboxylation by an α-
ketoacid dehydrogenase complex...
- Alpha-amino
acids can be
generated using the
uncatalyzed reaction between alpha-
ketoacids, amines, and
phenylboronic acid. Heck-type
cross coupling of phenylboronic...
- to an α-
ketoacid,
typically catalysed by a transaminase. The
reaction can be
generalised as such: R1-amino acid + R2-α-
ketoacid ⇌ R1-α-
ketoacid + R2-amino...
