- In
organic chemistry, keto
acids or
ketoacids (also
called oxo
acids or oxoacids) are
organic compounds that
contain a
carboxylic acid
group (−COOH) and...
-
decarboxylation of branched, short-chain alpha-
ketoacids.
BCKDC is a
member of the
mitochondrial α-
ketoacid dehydrogenase complex family,
which also includes...
-
aminotransferase (BCAT) into
their relevant α-
ketoacids. The
second step
involves the
conversion of α-
ketoacids into acetoacetate, acetyl-CoA, and succinyl-CoA...
-
generally caused when the body
produces an
excess amount of
organic acids (
ketoacids in ketoacidosis, or
lactic acid in
lactic acidosis). A
state of chronic...
- conditions,
excessive free
fatty acid
metabolism results in the
production of
ketoacids,
acetoacetic acid, and beta-hydroxybutyrate.
Lactic acidosis results from...
-
Ligations by
Decarboxylative Condensations ofN-Alkylhydroxylamines and α-
Ketoacids".
Angewandte Chemie. 118 (8): 1270–1274. doi:10.1002/ange.200503991. ISSN 0044-8249...
-
Transamination is a
chemical reaction that
transfers an
amino group to a
ketoacid to form new
amino acids.This
pathway is
responsible for the deamination...
- to an α-
ketoacid,
typically catalysed by a transaminase. The
reaction can be
generalised as such: R1-amino acid + R2-α-
ketoacid ⇌ R1-α-
ketoacid + R2-amino...
- are
converted to α-
ketoacids by
transamination and
eventually to isovaleryl-CoA
through oxidative decarboxylation by an α-
ketoacid dehydrogenase complex...
- acetyl-CoA.
Thiamine (T:) is the
active component for
decarboxylation of alpha-
ketoacids,
including pyruvate: T: + RC(O)CO2H → T=C(OH)R + CO2 T=C(OH)R + R'COOH...
