-
Kainic acid, or
kainate, is an acid that
naturally occurs in some seaweed.
Kainic acid is a
potent neuroexcitatory amino acid
agonist that acts by activating...
-
Kainate receptors, or
kainic acid
receptors (KARs), are
ionotropic receptors that
respond to the
neurotransmitter glutamate. They were
first identified...
- receptors: AMPA and
kainate receptors.
Willardiine analogs have been
developed that have
different binding affinities for the AMPA and
kainate receptors. These...
-
selective agonist for the AMPA receptor, with only
limited effects at the
kainate receptor. It is an
excitotoxic neurotoxin when used in vivo and so is rarely...
- of the AMPA and
kainate subtypes of the
ionotropic glutamate receptor family, with
selectivity for the GluR5
subtype of the
kainate receptor. It has...
- receptors, and
metabotropic glutamate receptors. A
fourth class,
known as
kainate receptors, are
similar in many
respects to AMPA receptors, but much less...
-
Glutamate receptor, ionotropic,
kainate 1, also
known as GRIK1, is a
protein that in
humans is
encoded by the GRIK1 gene. This gene
encodes one of the...
- has no
effect on
other glutamate receptors (such as
those for AMPA and
kainate). NMDA
receptors are
particularly important when they
become overactive...
- plasticity. They are
activated by the drug
kainate and are
permeable to both
sodium and pot****ium ions.
Kainate receptors are
expressed in a
variety of brain...
-
binding properties (pharmacology) and
sequence similarity: AMPA receptors,
kainate receptors, NMDA
receptors and
delta receptors (see below). AMPA receptors...
