-
Kainic acid, or
kainate, is an acid that
naturally occurs in some seaweed.
Kainic acid is a
potent neuroexcitatory amino acid
agonist that acts by activating...
-
Kainate receptors, or
kainic acid
receptors (KARs), are
ionotropic receptors that
respond to the
neurotransmitter glutamate. They were
first identified...
- been
traditionally classified as a non-NMDA-type receptor,
along with the
kainate receptor. Its name is
derived from its
ability to be
activated by the artificial...
- receptors, and
metabotropic glutamate receptors. A
fourth class,
known as
kainate receptors, are
similar in many
respects to AMPA receptors, but much less...
-
cyanquixaline (6-cyano-7-nitroquinoxaline-2,3-dione) is a
competitive AMPA/
kainate receptor antagonist. Its
chemical formula is C9H4N4O4. CNQX is
often used...
-
binding properties (pharmacology) and
sequence similarity: AMPA receptors,
kainate receptors, NMDA
receptors and
delta receptors (see below). AMPA receptors...
-
isolate the
action of
other glutamate receptors in the brain, i.e., AMPA and
kainate receptors. AP5 can
block the
conversion of a
silent synapse to an active...
- has no
effect on
other glutamate receptors (such as
those for AMPA and
kainate). NMDA
receptors are
particularly important when they
become overactive...
- receptors: AMPA and
kainate receptors.
Willardiine analogs have been
developed that have
different binding affinities for the AMPA and
kainate receptors. These...
-
damaged neurons.
Riluzole has also been
reported to
directly inhibit the
kainate and NMDA receptors. The drug has also been
shown to
postsynaptically potentiate...
