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Kainate receptors, or
kainic acid
receptors (KARs), are
ionotropic receptors that
respond to the
neurotransmitter glutamate. They were
first identified...
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Kainic acid, or
kainate, is an acid that
naturally occurs in some seaweed.
Kainic acid is a
potent neuroexcitatory amino acid
agonist that acts by activating...
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cyanquixaline (6-cyano-7-nitroquinoxaline-2,3-dione) is a
competitive AMPA/
kainate receptor antagonist. Its
chemical formula is C9H4N4O4. CNQX is
often used...
- receptors: AMPA and
kainate receptors.
Willardiine analogs have been
developed that have
different binding affinities for the AMPA and
kainate receptors. These...
- receptors, and
metabotropic glutamate receptors. A
fourth class,
known as
kainate receptors, are
similar in many
respects to AMPA receptors, but much less...
- AMPA
receptors in
micromolar concentrations (~10–20 μM) and also
blocks kainate receptors. In experiments, it is used to
counter glutamate excitotoxicity...
-
selective agonist for the
kainate receptor. This
potent agonist has
nearly 3,000 fold- and 200-fold
selectivity for
kainate receptors over AMPA and NMDA...
- UBP-302 is a
highly selective kainate receptor antagonist used in the
study of many
neurological processes. It is
active at
micromolar concentration within...
-
binding properties (pharmacology) and
sequence similarity: AMPA receptors,
kainate receptors, NMDA
receptors and
delta receptors (see below). AMPA receptors...
-
damaged neurons.
Riluzole has also been
reported to
directly inhibit the
kainate and NMDA receptors. The drug has also been
shown to
postsynaptically potentiate...
