- KIT
consists of an
extracellular domain, a
transmembrane domain, a
juxtamembrane domain, and an
intracellular tyrosine kinase domain. The extracellular...
- on
adjacent cells. p120 (sometimes
called delta catenin)
binds the
juxtamembrane region of the cadherin. γ-catenin or gamma-catenin (plakoglobin) binds...
-
creating a net
negative charge on MUC-1. The
smaller subunit contains a
juxtamembrane region of the
extracellular area, a
transmembrane domain, and the cytoplasmic...
- the FnIII-3
domain lies a
transmembrane helix (TH) and
intracellular juxtamembrane (JM) region, just
upstream of the
intracellular tyrosine kinase (TK)...
- cetuximab/Erbitux/IMC-C225 1z9i: A
Structural Model for the Membrane-Bound Form of the
Juxtamembrane Domain of the
Epidermal Growth Factor Receptor 2gs2:
Crystal Structure...
-
specific for
glucose and it
further transfers the
phosphoryl group to a
juxtamembrane EIIB. Finally, EIIB
phosphorylates glucose as it
crosses the plasma...
-
bonding phosphotyrosine residues on an Ac-LY****NPApY-NH2
peptide in the
juxtamembrane region of the
insulin receptor.
Further interactions via "bridged" water...
- in
binding signal transduction molecules have been
identified in the
juxtamembrane domain, the
kinase insert, and in the C-terminal tail in the PDGFβ receptor...
- PRRs are
composed of an
extracellular domain,
transmembrane domain,
juxtamembrane domain and
intracellular kinase domain as part of a
single protein....
-
structures (Ig domains), a
typical protein-protein
interaction region. A
juxtamembrane segment that contains: A
serine residue (Ser 985),
which inhibits the...