-
classical Isosteres are
molecules or ions with
similar shape and
often electronic properties. Many
definitions are available. but the term is usually...
- properties.
Alloxanthine is an
inhibitor of
xanthine oxidase. It is also an
isostere of xanthine, the
normal substrate for the enzyme.
Alloxanthine is considered...
-
compound can be
classified as a
cyclic amide, and as such is used as an
isostere for
peptides and
other pharmaceutically inspired targets. The 4-methyl-2-quinolone...
-
Quantitative Control of
Dihydrofolate Reductase Activity by
Using a
Photochromic Isostere of an Inhibitor". ChemBioChem. 20 (11): 1382–1386. doi:10.1002/cbic.201800816...
- is a
derivative of
anthranilic acid,: 235
which in turn is a
nitrogen isostere of
salicylic acid,
which is the
active metabolite of aspirin.: 235 Several...
- Non-canonical base
pairs are
planar hydrogen bonded pairs of nucleobases,
having hydrogen bonding patterns which differ from the
patterns observed in Watson-Crick...
-
require hematological monitoring.
Investigation on a
series of
thiophene isosteres on 1 of the
phenyl rings in clozapine, a
thienobenzodiazepine analog (olanzapine)...
- is a
derivative of
anthranilic acid,: 235
which in turn is a
nitrogen isostere of
salicylic acid,
which is the
active metabolite of aspirin.: 235 : 17 ...
-
coordination complexes. Erlenmeyer, H.; Schmid,
Erich H. (1939). "Über
isostere und strukturähnliche
Verbindungen XI.
Darstellung und
Eigenschaften des...
-
Quantitative Control of
Dihydrofolate Reductase Activity by
Using a
Photochromic Isostere of an Inhibitor". ChemBioChem. 20 (11): 1382–1386. doi:10.1002/cbic.201800816...
