-
Prenylation (also
known as
isoprenylation or lipidation) is the
addition of
hydrophobic molecules to a
protein or a biomolecule. It is
usually ****umed...
- to
enhance their attachment to the cell membrane; this is
known as
isoprenylation.
Terpenoids play a role in
plant defense as
prophylaxis against pathogens...
- (a type of acylation),
attachment of palmitate, a C16
saturated acid
isoprenylation or prenylation, the
addition of an
isoprenoid group (e.g.
farnesol and...
-
through four
steps of modification:
isoprenylation, proteolysis,
methylation and palmitoylation.
Isoprenylation involves the
enzyme farnesyltransferase...
- proteins.
Eukaryotic proteins undergo three modifications,
including isoprenylation,
proteolysis and methylesterification, and are
synthesised with the...
- geranylgeranylation, glutamylation, glycosylation, glycylation, hydroxylation,
isoprenylation, lactylation, lipoylation, methylation, nitroalkylation, phosphopantetheinylation...
- D-mannitol.
Alternative syntheses were
realized through the
asymmetric isoprenylation of
correspondent aldehyde (prenal) and
alcohol (prenol).
Chiral resolution...
- MT,
Kinsella BT (1999). "The
prostacyclin receptor is isoprenylated.
Isoprenylation is
required for
efficient receptor-effector coupling". J. Biol. Chem...
-
Inglese J,
Glickman JF,
Lorenz W,
Caron MG,
Lefkowitz RJ (January 1992). "
Isoprenylation of a
protein kinase.
Requirement of farnesylation/alpha-carboxyl methylation...
-
accomplishments from the Gelb
laboratory include: 1) The
discovery of
protein isoprenylation in the late 1980s (together with
Professor John Glomset); 2) The development...
