- An
isopeptidase is a
protease enzyme that
hydrolyzes isopeptide bonds, or
amide bonds that
occur outside the main
chain in a
polypeptide chain. Isopeptide...
-
strains of
yeast by the 26S
complex without affecting its
ATPase or
isopeptidase activities. MG132
activates c-Jun N-terminal
kinase (JNK1),
which initiates...
-
shown to be a
sensitive substrate for UCH-L3 (Km = 0.039 μM) and for
Isopeptidase-T (Km = 0.17-1.4 μM), and is
particularly useful for
studying deubiquitinylating...
- also
known as UBP43, is a type I
interferon receptor repressor and an
isopeptidase. In humans, it is
encoded by the USP18 gene. USP18 is
induced by the...
- peptidases,
deubiquitinating isopeptidases, deubiquitinases,
ubiquitin proteases,
ubiquitin hydrolases, or
ubiquitin isopeptidases, are a
large group of proteases...
- RJ (2017). "Capzimin is a
potent and
specific inhibitor of
proteasome isopeptidase Rpn11".
Nature Chemical Biology. 13 (5): 486–493. doi:10.1038/nchembio...
-
types of
reactions including deamidation, GTP-binding/hydrolyzing, and
isopeptidase activities.
Unlike other members of the
transglutaminase family, tTG...
- 314. PMID 8723724. "Entrez Gene: USP5
ubiquitin specific peptidase 5 (
isopeptidase T)". Rual JF,
Venkatesan K, Hao T, Hirozane-Kishikawa T,
Dricot A, Li...
- Co-crystal
structure of znf ubp
domain from the
deubiquitinating enzyme isopeptidase T (isot) in
complex with
ubiquitin 2gbj:
Crystal Structure of the 9-10...
-
intracellular targets.
These conjugates can be
reversed by UBL-specific
isopeptidases that have
similar mechanisms to that of the
deubiquitinating enzymes...
