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Isocitrate dehydrogenase (IDH) (EC 1.1.1.42) and (EC 1.1.1.41) is an
enzyme that
catalyzes the
oxidative decarboxylation of
isocitrate,
producing alpha-ketoglutarate...
- of
isocitric acid are
known as
isocitrates. The
isocitrate anion is a
substrate of the
citric acid cycle.
Isocitrate is
formed from
citrate with the...
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Isocitrate dehydrogenase [NADP],
mitochondrial is an
enzyme that in
humans is
encoded by the IDH2 gene.
Isocitrate dehydrogenases are
enzymes that catalyze...
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Isocitrate lyase (EC 4.1.3.1), or ICL, is an
enzyme in the
glyoxylate cycle that
catalyzes the
cleavage of
isocitrate to
succinate and glyoxylate. Together...
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certain forms of glioma.
Vorasidenib is a dual
mutant isocitrate dehydrogenase 1 and
isocitrate dehydrogenase 2 (mIDH1/2) inhibitor. The most
common adverse...
- In
recent years, however, the
detection of
malate synthase (MS) and
isocitrate lyase (ICL), key
enzymes involved in the
glyoxylate cycle, in some animal...
-
enzyme that
catalyses the stereo-specific
isomerization of
citrate to
isocitrate via cis-aconitate in the
tricarboxylic acid cycle, a non-redox-active...
- (specifically a
neomorphic one) in
isocitrate dehydrogenase (IDH) (which
under normal cir****stances
catalyzes the
oxidation of
isocitrate to oxalosuccinate, which...
-
Isocitrate dehydrogenase 1 (NADP+),
soluble is an
enzyme that in
humans is
encoded by the IDH1 gene on
chromosome 2.
Isocitrate dehydrogenases catalyze...
-
Isocitrate lyase family is a
family of
evolutionarily related proteins.
Isocitrate lyase (EC 4.1.3.1) is an
enzyme that
catalyzes the
conversion of isocitrate...
