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Islatravir (4′-ethynyl-2-fluoro-2′-deoxyadenosine, EFdA, or MK-8591) is an
investigational drug for the
treatment of HIV infection. It is
classified as...
- This is a new
class of antivirals, MK-8591 or
Islatravir being the
first agent of this group.
Islatravir was
developed by
Merck & Co. It is
orally available...
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neutralizing antibodies teropavimab and
zinlirvimab as well as
lenacapavir with
islatravir. In July 2024, a
study reported 100%
efficacy for pre-exposure HIV prevention...
- was used in a
mixture of five
enzymes in the
biocatalytic synthesis of
islatravir. DERA has also been used to
perform tandem aldol reactions with three...
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Zidovudine (AZT, ZDV)# Amdoxovir† Apricitabine† Censavudine† Elvucitabine†
Islatravir (EFdA, ISL)§ Racivir† Stampidine†
Nucleotide analogues/NtRTIs: Tenofovir...
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Zidovudine (AZT, ZDV)# Amdoxovir† Apricitabine† Censavudine† Elvucitabine†
Islatravir (EFdA, ISL)§ Racivir† Stampidine†
Nucleotide analogues/NtRTIs: Tenofovir...
-
Zidovudine (AZT, ZDV)# Amdoxovir† Apricitabine† Censavudine† Elvucitabine†
Islatravir (EFdA, ISL)§ Racivir† Stampidine†
Nucleotide analogues/NtRTIs: Tenofovir...
-
inhibitors which can be
administered by
injection every 6 months) and
Islatravir, from
Merck (which
belongs to a new
class of ARV
drugs called nucleoside...