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Disacquaint
Disacquaint Dis`ac*quaint", v. t. [Pref. dis- + acquaint: cf.
OF. desacointier.]
To render unacquainted; to make unfamiliar. [Obs.]
While my sick heart With dismal smart Is disacquainted
never. --Herrick.
Disacquaintance
Disacquaintance Dis`ac*quaint"ance, n.
Neglect of disuse of familiarity, or familiar acquaintance.
[Obs.] --South.
Meaning of Isacq from wikipedia