-
linkage between them. This
crosslink can
occur within the same
strand (
intrastrand) or
between opposite strands of double-stranded DNA (interstrand). These...
- crosslinks,
intrastrand crosslinks or DNA
protein crosslinks.
Mostly they act on the
adjacent N-7
position of guanine,
forming a 1, 2
intrastrand crosslink...
-
notable among the
changes in DNA are the 1,2-
intrastrand cross-links with
purine bases.
These include 1,2-
intrastrand d(GpG) adducts,
which form
nearly 90% of...
- from the
diversity and
degree of
crosslinking between these lignols.
Intrastrand DNA
crosslinks have
strong effects on
organisms because these lesions...
- P.
putida KT2440
chromosome is
characterized by
strand symmetry and
intrastrand parity of
complementary oligonucleotides. Each
tetranucleotide occurs...
-
Povirk LF (March 1997). "Specificity and
kinetics of
interstrand and
intrastrand bifunctional alkylation by
nitrogen mustards at a G-G-C sequence". Nucleic...
-
variety of DNA
damage products such as mono- and dialkylation, inter- and
intrastrand crosslinks, and DNA-protein crosslinks. Some of the
substances require...
- this double-stranded (dsDNA)
structure is
maintained largely by the
intrastrand base
stacking interactions,
which are
strongest for G,C stacks. The two...
-
strands and the
molecules may
either bind
twice to one
strand of DNA (
intrastrand crosslink) or may bind once to both
strands (interstrand crosslink)....
-
leaving group. DNA
crosslinking prevents DNA replication.
Because the
intrastrand DNA
crosslinks cannot be
repaired by
cellular machinery, the cell undergoes...
