-
strand (intrastrand) or
between opposite strands of double-stranded DNA (
interstrand).
These adducts interfere with
cellular metabolism, such as DNA replication...
-
chlorine forms the
second alkylation step that
results in the
formation of
interstrand cross-links (ICLs) as it was
shown in the
early 1960s. At that time,...
- β-chloro-nitrosourea compound. As an
alkylating agent,
carmustine can form
interstrand crosslinks in DNA,
which prevents DNA
replication and DNA transcription...
- PMID 17978187.
Marchetti F,
Bishop J,
Gingerich J,
Wyrobek AJ (2015). "Meiotic
interstrand DNA
damage escapes paternal repair and
causes chromosomal aberrations...
- Mason,
Tracey Mcgregor; Miller, Paul S. (2006). "Formation and
Repair of
Interstrand Cross-Links in DNA".
Chemical Reviews. 106 (2): 277–301. doi:10.1021/cr040478b...
- XPF are
especially sensitive to
agents that
cause DNA
interstrand crosslinks (ICL)
Interstrand crosslinks block the
progression of DNA replication, and...
- PMID 11226027.
Marchetti F,
Bishop J,
Gingerich J,
Wyrobek AJ (2015). "Meiotic
interstrand DNA
damage escapes paternal repair and
causes chromosomal aberrations...
- Noll DM,
Mason TM,
Miller PS (February 2006). "Formation and
repair of
interstrand cross-links in DNA".
Chemical Reviews. 106 (2): 277–301. doi:10.1021/cr040478b...
-
Repair of DNA in
which the two
complementary strands are
joined by an
interstrand covalent crosslink requires multiple incisions in
order to disengage...
-
major DNA
repair pathway that
mainly acts on double-strand
breaks and
interstrand crosslinks Hondo Railway, an
American railway Horuru language, dialect...
