-
Genetic variation is the
difference in DNA
among individuals or the
differences between po****tions
among the same species. The
multiple sources of genetic...
-
Interindividual differences in
perception describes the
effect that
differences in
brain structure or
factors such as culture,
upbringing and environment...
- von
Moltke LL, et al. (April 2004). "Pharmacogenetic
determinants of
interindividual variability in
bupropion hydroxylation by
cytochrome P450 2B6 in human...
- promoter; however, some are in the 5' UTR as well and
there is a lot of
interindividual variability in the
cytosine methylation in
these regions. A
study in...
- the role of
glycine N-acyltransferase, and
factors that
influence interindividual variation".
Expert Opinion on Drug
Metabolism & Toxicology. 9 (9):...
- the role of
glycine N-acyltransferase, and
factors that
influence interindividual variation".
Expert Opinion on Drug
Metabolism & Toxicology. 9 (9):...
- ℞ (Prescription only)
Pharmacokinetic data
Bioavailability 10–80% (Oral;
large interindividual variation)
Protein binding 90–99%
Metabolism Liver,
mostly CYP2D6-mediated...
- not vary by
route of administration, but is
subject to
substantial interindividual variability. CYP2D6,
dopamine β-hydroxylase, flavin-containing monooxygenase...
- "Body
surface area-based
dosing of 5-fluoruracil
results in
extensive interindividual variability in 5-fluorouracil
exposure in
colorectal cancer patients...
-
concentrations of
trazodone or mCPP. In any case,
there are
large interindividual variations in the
metabolism of trazodone. In addition, poor metabolizers...
