-
interferons is to up-regulate
major histocompatibility complex molecules, MHC I and MHC II, and
increase immunoproteasome activity. All
interferons significantly...
- (IFNE), IFNк (IFNK) and IFNβ (IFNB1), plus 11 IFN pseudogenes.
Interferons bind to
interferon receptors. All type I IFNs bind to a
specific cell
surface receptor...
-
reduction in the rate of MS relapses.
Interferon beta has not been
shown to slow the
advance of disability.
Interferons are not a cure for MS (there is no...
- An
interferon-stimulated gene (ISG) is a gene that can be
expressed in
response to
stimulation by
interferon.
Interferons bind to
receptors on the surface...
- for type I
interferons, IFNLR1 is
largely restricted to
tissues of
epithelial origin.
Despite high
homology between type III
interferons, the binding...
-
Pegylated interferon (PEG-IFN) is a
class of
medication that
includes three different drugs as of 2012:
Pegylated interferon-alpha-2a
Pegylated interferon-alpha-2b...
-
Interferon gamma (IFNG or IFN-γ) is a
dimerized soluble cytokine that is the only
member of the type II
class of
interferons. The
existence of this interferon...
- II
interferons help to
modulate the
immune system’s
response to pathogens, and
these interferons also
respond to pathogens. Type III
interferons induce...
-
signaling as
immunomodulating agents.
Cytokines include chemokines,
interferons, interleukins, lymphokines, and
tumour necrosis factors, but generally...
- non-responders to
interferon beta-1b.
While more
studies of the long-term
effects of the
drugs are needed, some data on the
effects of
interferons indicate that...
