-
Integrins are
transmembrane receptors that help cell–cell and cell–extracellular
matrix (ECM) adhesion. Upon
ligand binding,
integrins activate signal...
- to
integrin α4β7 (LPAM-1,
lymphocyte Peyer's
patch adhesion molecule 1, a
dimer of
Integrin alpha-4 and
Integrin beta-7),
blocking the α4β7
integrin results...
- with
integrin alpha 1 and
integrin alpha 2 to form
integrin complexes which function as
collagen receptors. It also
forms dimers with
integrin alpha...
- also
known as
Integrin,
alpha X (complement
component 3
receptor 4 subunit) (ITGAX), is a gene that
encodes for CD11c . CD11c is an
integrin alpha X chain...
-
Integrin beta-7 is an
integrin protein that in
humans is
encoded by the ITGB7 gene. It can pair with ITGA4 (CD49d) to form the
heterodimeric integrin...
- In cell biology, CD11 is the α (alpha)
component of
various integrins,
especially ones in
which the β (beta)
component is CD18 (β2) and
mediate leukocyte...
-
Integrin alpha M (ITGAM) is one
protein subunit that
forms heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also
known as macrophage-1
antigen (Mac-1)...
- In
molecular biology, CD18 (
Integrin beta chain-2) is an
integrin beta
chain protein that is
encoded by the ITGB2 gene in humans. Upon
binding with one...
- medicine,
glycoprotein IIb/IIIa (GPIIb/IIIa, also
known as
integrin αIIbβ3) is an
integrin complex found on platelets. It is a
transmembrane receptor...
-
matrix such as
fibronectin and
hyaluronan can also bind to such
receptors (
integrins and CD44, respectively). In addition, some
molecules such as
steroid hormones...
