-
Retroviral integrase (IN) is an
enzyme produced by a
retrovirus (such as HIV) that
integrates (forms
covalent links between) its
genetic information into...
-
Integrase inhibitors (INIs) are a
class of
antiretroviral drug
designed to
block the
action of
integrase, a
viral enzyme that
inserts the
viral genome...
-
usually identical, but
there are
exceptions (e.g. attP and attB of λ
integrase).
Based on
amino acid
sequence homologies and
mechanistic relatedness...
-
version of its
genome into the host cell DNA is
called its "
integrase". HIV-1
integrase catalyzes the “cut-and-paste”
action of
clipping the host DNA...
- It
contains bictegravir, a
human immunodeficiency virus type 1 (HIV-1)
integrase strand transfer inhibitor; emtricitabine, an HIV-1
nucleoside analog reverse...
- (backward). The new DNA is then
incorporated into the host cell
genome by an
integrase enzyme, at
which point the
retroviral DNA is
referred to as a provirus...
- to NNRTIs.
Integrase inhibitors (also
known as
integrase nuclear strand transfer inhibitors or INSTIs)
inhibit the
viral enzyme integrase,
which is responsible...
- cell
nucleus and
integrated into the
cellular DNA by a
virally encoded integrase and host co-factors. Once integrated, the
virus may
become latent, allowing...
- (insufflation), a
method of
administrating some
medications and
vaccines Integrase, a
retroviral enzyme In (album), by the Outsiders, 1967 In (Korean name)...
-
resistance to non-nucleoside
reverse transcriptase inhibitors (NNRTIs) and
integrase strand transfer inhibitors. Cabotegravir/rilpivirine must not be combined...
