Definition of Inflammasomes. Meaning of Inflammasomes. Synonyms of Inflammasomes

- Inflammasomes are cytosolic multiprotein complexes of the innate immune system responsible for the activation of inflammatory responses and cell death...
- activating STAT6 and SPDEF. Mutations in the NLRP3 gene result in autoactive inflammasomes and have been ****ociated with a spectrum of dominantly inherited autoinflammatory...
- or NLRC4 (NOD-like receptors (NLR) Family CARD Domain Containing 4). Inflammasomes are cytoplasmic protein complexes that can generate active, secreted...
- formation of multi-protein complex inflammasomes, which then activates caspases to initiate pyroptosis. The inflammasome pathway may be canonical or noncanonical...
- of covalent NLRP3 inflammasome inhibitors: Chemistry and biological activity". Archives of Biochemistry and Biophysics. Inflammasomes: Intracellular mediators...
- NLRC4 as proximal components of inflammasomes responsible for caspase-1 activation. The research showed that inflammasomes distinguish between inflammatory...
- inflammasomes. Caspase-1, normally in its physiologically inactive zymogen form, autoactivates when it is ****embled into the filamentous inflammasome...
- (by acting as an electron acceptor), and decreases the activation of inflammasomes NLRP3 and NLRC4. As a result, it's been considered potentially useful...
- towards neuroinflammation as Aβ buildup can further activate additional inflammasomes. NLRP3 activation can also arise from hyperphosphorylated tau, and can...
- autoimmune inflammation Different inflammasome complex — cytosolic molecular complex — have been described. Inflammasomes recognize danger signals and activate...