-
Indolizidine is a
heterocyclic chemical compound that
forms the
central core of the
indolizidine alkaloids such as
swainsonine and castanospermine. Indole...
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Indolizidine alkaloids are
natural products from
various alkaloid groups whose structure can be
derived from
indolizidine.
Indolizidine alkaloids are...
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nitrogen located at a ring
fusion position. The
saturated analogs are
indolizidine,
which are
found in a
variety of
alkaloids such as swainsonine. Examples...
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Swainsonine is an
indolizidine alkaloid. It is a
potent inhibitor of
Golgi alpha-mannosidase II, an immunomodulator, and a
potential chemotherapy drug...
- 93 Aniszewski, p. 98 Saxton, Vol. 1, p. 91
Joseph P.
Michael (2002). "
Indolizidine and
quinolizidine alkaloids". Nat. Prod. Rep. 19 (5): 458–475. doi:10...
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Castanospermine is an
indolizidine alkaloid first isolated from the
seeds of
Castanospermum australe. It is a
potent inhibitor of some
glucosidase enzymes...
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Mitragynine pseudoindoxyl is a
rearrangement product of 7-hydroxymitragynine, an
active metabolite of mitragynine.
Mitragynine pseudoindoxyl can be produced...
-
cyclization of
ketene dithioacetals. A
general synthesis of pyrrolizidine,
indolizidine, and
quinolizidine alkaloid ring systems". J. Org. Chem. 49 (10): 1682...
- 339A has an
axially oriented hydroxyl group at the 7-position in the
indolizidine nucleus that
differentiates it from
allopumiliotoxin 339B. A (+) or (−)...
- 2, 2017.
Jones et al. (1997), page 752.
Michael JP (December 1997). "
Indolizidine and
quinolizidine alkaloids".
Natural Product Reports. 14 (6): 619–36...