- (FK506),
which inhibit the
prolyl isomerase activity of the
immunophilins. The drug-
immunophilin complexes (CsA-CyP and FK506-FKBP) bind to calcineurin, which...
-
exhibits protein phosphatase 2C
enzymatic activity, and the dual-family
immunophilins that
occur in a
number of
unicellular organisms (such as
protozoan parasites...
- groups:[citation needed]
glucocorticoids cytostatics antibodies drugs acting on
immunophilins other drugs In
pharmacologic (supraphysiologic) doses, glucocorticoids...
- (December 1992). "Structural and
evolutionary relationships among the
immunophilins: two
ubiquitous families of peptidyl-prolyl cis-trans isomerases". FASEB...
- that is
responsible for the
interaction with co-factors such as the
immunophilins FKBP51 and FKBP52, the
stress induced phosphoprotein 1 (Sti1/Hop), cyclophilin-40...
- is
helpful with
autoimmune diseases|, Alternatively,
inhibitors of
immunophilins more
specifically target T
lymphocyte activation, the
process by which...
- (may be pseudogene): FKBP1C
Pseudogenes in humans: LOC541473; FKBP9L;
Immunophilins Siekierka JJ, Hung SH, Poe M, Lin CS,
Sigal NH (October 1989). "A cytosolic...
-
around the heat
shock protein 90 (HSP90),
containing p23 protein, and
immunophilin, and
located in
majority in
cytoplasm and
partially in nucleus. In the...
-
tacrolimus reduces peptidylprolyl isomerase activity by
binding to the
immunophilin FKBP12 (FK506
binding protein),
creating a new complex. This FKBP12–FK506...
-
cytoplasm and form
multiprotein complexes with heat
shock proteins (HSPs),
immunophilins, and
other chaperones such as src, and p23. The GR acts in a ligand-dependent...
