- An
iminosugar, also
known as an iminosaccharide, is any
analog of a
sugar where a
nitrogen atom has
replaced the
oxygen atom in the ring of the structure...
- N-acetylation will
furnish the
desired 2-N-acetamido-2-deoxyglycosides.
Iminosugar N-Acetylglucosamine
Galactosamine Glucosamine Sialic acid L-Daunosamine...
-
strains of streptomycetes, e.g.
Streptomyces azureus. Nojirimycin, an
iminosugar from a
class of
Streptomyces species. Tetrodotoxin, a
neurotoxin produced...
- gardens.
Members of this
genus ac****ulate
hydroxypipecolic acids and
iminosugars in
their leaves.
Xanthocercis Baill.
Plants of the
World Online. Retrieved...
-
mainly obtained from a
class of
Streptomyces species. Chemically, it is an
iminosugar. 1-deoxynojirimycin or
duvoglustat 1-deoxygalactonojirimycin or migalastat...
- doesn't work; this is
called substrate reduction therapy.
Miglustat is an
iminosugar, a
synthetic analogue of D-glucose and a
white to off-white crystalline...
-
Castanospermine is an
indolizidine alkaloid first isolated from the
seeds of
Castanospermum australe. It is a
potent inhibitor of some
glucosidase enzymes...
- due to
various mutations, one of
which is
called N370S. A****ostat, an
iminosugar,
binds selectively to N370S
glucocerebrosidase and
restores its correct...
-
Swainsonine is an
indolizidine alkaloid. It is a
potent inhibitor of
Golgi alpha-mannosidase II, an immunomodulator, and a
potential chemotherapy drug...
- 1-Deoxynojirimycin (DNJ or 1-DNJ), also
called duvoglustat or moranolin, is an alpha-glucosidase inhibitor, most
commonly found in
mulberry leaves. Although...
